Metabolomic Analysis of Liver Tissue from the VX2 Rabbit Model of Secondary Liver Tumors
Figure 1
Power analyses and sample size calculations. The plots show statistical power curves () for the main treatment effect (tumor versus control Gelfoam) as a function of group sample size (n g). Results are reported for a range of fixed fold change, for the fixed estimated median standard deviation common to all metabolites , and for fixed , while controlling the False Discovery Rate at 10%. Results show that a group sample size of n g = 5 in a balanced paired experimental design detects a twofold change in the effect of interest with more than 90% power.
