Preoperative Gadoxetic Acid-Enhanced MRI and Simultaneous Treatment of Early Hepatocellular Carcinoma Prolonged Recurrence-Free Survival of Progressed Hepatocellular Carcinoma Patients after Hepatic Resection

Table 3

Univariate analysis of pathological and tumor-related factors for overall and recurrence-free survival after hepatic resection for HCC.

Variable	Number of patients	Overall survival			Recurrence-free survival
		HR	95% CI	𝑃 value	HR	95% CI	𝑃 value
Diameter of main tumor (cm)
≦2.0	39	1			1
>2.0	108	1.11	0.50–2.46	0.79	1.39	0.84–2.30	0.19
Number of advanced HCCs
Solitary	110	1			1
Multiple	37	1.26	0.60–2.62	0.54	1.96	1.22–3.14	<0.01
Fibrous capsule formation
Absent	34	1			1
Present	113	1.18	0.51–2.70	0.7	1.26	0.57–2.12	0.39
Vessel invasion
Absent	115	1			1
Present	32	0.95	0.43–2.10	0.9	1.03	0.62–1.71	0.91
Pathological diagnosis
Well or moderate	118	1			1
Poor	29	1.68	0.78–3.62	0.18	1.02	0.59–1.75	0.95
AJCC stage
I	90	1			1
II or III	57	1.29	0.67–2.49	0.45	1.29	0.83–1.98	0.25
Liver cirrhosis
Absent	70	1			1
Present	77	2.58	1.23–5.38	0.01	1.23	0.81–1.89	0.34