Table 4: Impact of HPV vaccines according to age specific HPV prevalence.
(a) Cervical cancer incident cases
Country
Group of age
Total*
50
50–59
60
Colombia, Cali
489
217
339
1045
Uganda, Kyadondo County
313
69
70
452
USA, Connecticut
382
52
46
480
(b) Expected incident cases and estimated impact of vaccination
Case
50
50–59
60
Impact based on global estimates
Impact based on age-specific estimates
HPV 16,18
Attributable cases (%)
65.5
77.1
46.3
63.2
—
Colombia, Cali
169
50
182
63.2
61.7
Uganda, Kyadondo County
108
16
38
63.2
64.3
USA, Connecticut
132
12
25
63.2
64.9
HPV 16,18,45
Attributable cases (%)
79.8
79.4
48.6
71.4
—
Colombia, Cali
99
45
174
71.4
69.6
Uganda, Kyadondo County
63
14
36
71.4
74.9
USA, Connecticut
77
11
24
71.4
76.8
HPV 16,18,45,31
Attributable cases (%)
85.2
80.6
58.4
76.8
—
Colombia, Cali
72
42
141
76.8
75.6
Uganda, Kyadondo County
46
13
29
76.8
80.3
USA, Connecticut
57
10
19
76.8
82.1
HPV 16,18,45,58
Attributable cases (%)
81.6
87.4
60.6
77.3
—
Colombia, Cali
90
27
134
77.3
76.0
Uganda, Kyadondo County
58
9
28
77.3
79.2
USA, Connecticut
70
7
18
77.3
80.2
Incident cases in (a) based on 28. Attributable cases based on study results. Numbers for each country in (b) correspond to the expected number of cases given the percentage of attributable cases. The impact based on global estimates was obtained from cumulative percentages in Figure 1(a). The impact based on age-specific estimates corresponds to the reduction in number of cases as percentage of the initial number of cases, obtained from the summatory of expected cases in age groups (50, 50–59, 60). Single infections assumed after distribution of multiple infections.
*Total cases do not include unknown age.