Pretreatment with Pancaspase Inhibitor (Z-VAD-FMK) Delays but Does Not Prevent Intraperitoneal Heat-Killed Group B Streptococcus-Induced Preterm Delivery in a Pregnant Mouse Model

<table><i>Apoptosis in the ovarian follicle</i>. Mouse atretic follicles are known to undergo caspase mediated apoptosis. As anticipated, caspase 3 was cleaved and activated in the atretic follicle, which were used as positive control for the caspase 3 antibody specificity. Representative data from three separate experiments are shown.</table>

Infectious Diseases in Obstetrics and Gynecology

fig4

Figure 4

Figure 4: Pretreatment with Pancaspase Inhibitor (Z-VAD-FMK) Delays but Does Not Prevent Intraperitoneal Heat-Killed Group B Streptococcus-Induced Preterm Delivery in a Pregnant Mouse Model 

Figure 4 | Pretreatment with Pancaspase Inhibitor (Z-VAD-FMK) Delays but Does Not Prevent Intraperitoneal Heat-Killed Group B Streptococcus-Induced Preterm Delivery in a Pregnant Mouse Model 