Pretreatment with Pancaspase Inhibitor (Z-VAD-FMK) Delays but Does Not Prevent Intraperitoneal Heat-Killed Group B Streptococcus-Induced Preterm Delivery in a Pregnant Mouse Model : Table 1

]>Pretreatment with Pancaspase Inhibitor (Z-VAD-FMK) Delays but Does Not Prevent Intraperitoneal Heat-Killed Group B Streptococcus-Induced Preterm Delivery in a Pregnant Mouse Model : Table 1

Table 1: Intraperitoneal HK-GBS injection leads to preterm delivery, and pretreatment with Z-VAD-FMK delays preterm delivery in mice. 10⁹ heat killed GBS bacteria were injected intraperitoneally in day 14.5 pregnant CD-1 mice. Data from animals treated with HK-GBS without Z-VAD-FMK (GBS alone, PBS GBS or DMSO GBS) were combined.


	Preterm delivery 18 hours ()	Preterm delivery 18–24 hours ()	Preterm delivery 24–36 hours ()

GBS (n 14)	12 (86)	0	2 (14)
Z-VAD GBS (n 6)	1 (17)	2 (33)	3 (50)
P-value	.0072	.079	.13