Clinical Study

Association of Low-Risk Human Papillomavirus Infection with Male Circumcision in Young Men: Results from a Longitudinal Study Conducted in Orange Farm (South Africa)

Table 1

Background characteristics, reported sexual behaviour, and HIV, HSV-2 and low-risk HPV prevalence of the study population.

Control
Intervention
(1)

Background Characteristics
 Ethnic group (%)
  Sotho
  Zulu
  Other
53.2
33.1
13.7
54.2
28.3
17.5
.02
 Lives with a partner (%) (2)4.75.5.61
 Aged 21 and older (%)50.155.1.04
 Primary level of education completed (%)98.8(98.0).18

Reported sexual behaviour
 Mean (median) number of lifetime partners4.3 (4.0)4.4 (4.0).33
 Had at least one sexual partnership in the past 12 months (%)71.277.9.004
 Mean (median) number of partnerships in the past 12 months (2)1.4 (1.0)1.3 (1.0).70
 Mean (median) number of sexual intercourses in the past 12 months (2)13.3 (5.0)13.9 (6.0).41
 Consistent condom use in the past 12 months (%) (2)23.624.9.70

Sexually transmitted infection prevalence at the 21-month visit
 HIV positive (%)7.24.6.03
 HSV-2 positive (%)8.610.6.17
 Low-risk HPV positive (23 genotypes) (%)15.8 ( )8.5 ( )<.001
 Low-risk HPV positive (11 genotypes) (%)12.4 ( )6.6 ( )<.001

(1) Fisher’s exact for percentage comparison and Mann-Whitney test for mean comparison;
(2) among those having at least one sexual intercourse in the past 12 months (437 control and 497 intervention participants).