Imiquimod 3.75% Cream Applied Daily to Treat Anogenital Warts: Combined Results from Women in Two Randomized, Placebo-Controlled Studies

Table 4

Summary of local skin reactions, maximum intensity during evaluation period.

	Placebo	Imiquimod 2.5%	Imiquimod 3.75%
Women	105^a	193^a	203^a
Local skin reaction (LSR), 𝑛 (%)
Any LSR grade other than none	35 (33.3)	135 (69.9)	156 (76.8)
Severe grade
Any	1 (1.0)	26 (13.5)	36 (17.7)
Erythema	0 (0)	18 (9.3)	20 (9.9)
Edema	0 (0)	5 (2.6)	4 (2.0)
Weeping/exudates	0 (0)	1 (0.5)	2 (1.0)
Flaking/scaling/dryness	0 (0)	2 (1.0)	0 (0)
Scabbing/crusting	0 (0)	0 (0)	1 (0.5)
Erosion/ulceration	1 (1.0)	17 (8.8)	26 (12.8)

^aDenominator is the number of women with at least 1 postbaseline assessment.