Research Article

Clinicopathological Comparison of Adenocarcinoma of Cervix and Endometrium Using Cell Cycle Markers: P16ink4a, P21waf1, and p27Kip1 on 132 Cancers

Table 1

Summary of the clinicopathological parameters in adenocarcinoma of the cervix (ECA) and adenocarcinoma of the endometrium (EMA).

Variables of ECAFrequency (%) of ECAVariables of EMAFrequency (%) of EMA

Age (years)Age (years)
<353 (7.5) <5028 (30.4)
35–5422 (55.0)  50–6035 (38.0)
≥5515 (37.5)  >6029 (31.5)

FIGO stageFIGO stage
I27 (57.5)  I50 (54.3)
ll7 (17.5)  II13 (14.1)
lll5 ((12.5)  lll13 (14.1)
IV5 (12.5)  lV16 (17.4)

Histology tumor differentiationMyometrial invasion
Well/moderate25 (62.5)  < 45 (48.9)
Poor and Special type15 (37.5)  > 47 (51.1)

Infiltration depthHistologic grade
Inner 2/313 (32.5)  G139 (42.4)
Outer 1/3 or through27 (67.5)  G223 (25.0)
 G330 (32.6)

Tumor lengthPostmenopausal status
<20 mm11 (32.5)  Yes54 (58.7)
>20 mm29 (67.5)  No38 (41.3)

Tumor thickness
<5 mm4 (10.0)
>5 mm36 (90.0)

Infiltration to corpus
Yes17 (42.5)
No23 (57.5)

Vascular invasion
Yes20 (50.0)
No20 (50.0)

Lymph node invasion
 Yes12 (30.0)
 No28 (70.0)

Histologic type:Histologic type:
 Endocervical NOS25 (62.5) Endometrioid75 (81.5)
 Adenosquamous6 (15.0) Adenosquamous4 (4.4)
 Endometrioid5 (12.5) Clear cell5 (5.4)
 Serous1 (2.5) Serous5 (5.4)
  “Mixed”2 (5.0)  “Mixed”3 (3.3)