Atypical Squamous Cells of Undetermined Significance: Bethesda Classification and Association with Human Papillomavirus

Table 3

Results of biopsies performed on patients with an initial diagnosis of ASCUS who, upon review, were reclassified as having normal/inflammatory cytology, probably reactive ASCUS, and probably neoplastic ASCUS, and who, in accordance with the Regione Emilia Romagna (ASCUS 1 to 5), showed evidence of changes in the colposcopic exam.

	Cytology
Biopsy	Normal/inflammatory 𝑁 (%)	ASCUS
		Probably reactive 𝑁 (%)	Probably neoplastic 𝑁 (%)	1 𝑁 (%)	2 𝑁 (%)	3 𝑁 (%)	4 𝑁 (%)	5 𝑁 (%)
Normal	6 (20.0)	7 (18.4)	9 (28.1)	1 (6.6)	5 (26.3)	5 (26.3)	4 (25.0)	1 (100.0)
HPV/CINI	2 (6.6)	1 (2.6)	7 (21.8)	2 (13.3)	4 (21.0)	2 (10.5)	0	0
CIN II/III	0	1 (2.6)	5 (15.6)	3 (20.0)	2 (10.5)	0	1 (6.25)	0
Not performed	22 (73.3)	29 (76.3)	11 (34.3)	9 (60.0)	8 (42.1)	12 (63.1)	11 (68.7)	0
Total cases by group	30	38	32	15	19	19	16	1

All 𝑃s>.05; Fisher’s exact test.