Atypical Squamous Cells of Undetermined Significance: Bethesda Classification and Association with Human Papillomavirus

Table 4

Results of the biopsies performed on the total group of patients with an initial diagnosis of ASCUS who, after review, were reclassified as having cytologies that were normal/inflammatory, ASC-US, and ASC-H, which showed changes in the colposcopic examination.

	Cytology
Biopsy	Normal/inflammatory 𝑁 (%)	ASCUS
		ASC-US 𝑁 (%)	ASC-H 𝑁 (%)
Normal	6 (20.0)	13 (21.0)	3 (37.5)
HPV/CIN I	2 (6.6)	8 (13.0)	0
CIN II/III	0	1 (1.6)	5 (62.5)*
Not performed	22 (73.3)	40 (64.5)	0
Total cases by group	30	62	8

* 𝑃=.0256 and 𝑃=.0021, relative to ASC-US group, versus ASC-H group with normal/inflammatory cytology and cases of CIN II/III in biopsies of patients with ASC-H, respectively, Fisher’s exact test.