|
ORFa |
Gene | Molecular functionb | Log phase cocultures |
Late log to early stationary phase cocultures |
GR1_a | RC14_a | GR1_b | GR1_c | GR1_d | RC14_b | GR1_e |
|
Adhesionc | | | | | | | |
orf19.2122* | ALS12
*
| ALS family protein; role in adhesion, biofilm formation, germ tube induction* | −1.84 | −3.38# | 0.64 | 1.51 | −3.68# | −0.73 | −3.71# |
|
Amino acid metabolism | | | | | | | |
orf19.646 | GLN1 | Putative glutamate synthase | −3.16# | −0.50 | 0.45 | 1.56 | −1.62 | −3.20# | −3.08# |
orf19.3846 | LYS4 | Homoaconitase | −2.68 | −1.54 | 0.63 | −4.04# | −5.51# | −4.80# | −0.52 |
orf19.2360 | URA2 | Putative bifunctional carbamoylphosphate synthetase-aspartate transcarbamylase | −0.58 | −5.46# | −0.75 | −1.48 | −3.62# | −4.30# | −0.13 |
orf19.6257 | GLT1 | Putative glutamate synthase | −0.80 | −3.46# | 0.19 | −3.07# | −5.30# | −3.61# | 0.29 |
|
Cell wall organization | | | | | | | |
orf19.386 | SAM4 | Putative S-adenosylmethionine-homocysteine methyltransferase | −1.87 | −1.60 | 0.64 | −3.11# | −3.40# | −4.50# | −2.44 |
orf19.3829* | PHR1
*
| Glycosidase of cell surface* | −4.84# | −4.20# | −3.95# | −7.74# | −3.17# | −6.66# | −5.39# |
orf19.5171 | PMT1 | Protein mannosyltransferase, | −0.75 | −0.20 | 0.42 | −4.18# | −3.67# | −4.02# | −0.86 |
|
Cytoskeleton organization | | | | | | | |
orf19.2286 | | Putative deoxyhypusine hydroxylase | −2.97 | 0.36 | −1.06 | −1.51 | −3.07# | −3.08# | −3.49# |
|
DNA replication | | | | | | | |
orf19.5183* | POL3
*
| Large subunit of DNA polymerase III* | −2.60 | −4.03# | 0.98 | −0.12 | −4.07# | −3.39# | −2.58 |
orf19.6078 | POL93 | Putative gypsy-like reverse transcriptase | −3.48# | −0.48 | −0.43 | −6.24# | −1.66 | −4.44# | 0.28 |
orf19.2885* | PRI2
*
| Putative DNA primase* | 0.27 | −3.17# | −3.27# | −3.20# | 0.35 | −2.05 | 0.31 |
orf19.3322 | DUT1 | dUTP pyrophosphatase | −3.24# | −4.14# | −0.28 | −2.23 | −3.38# | −4.36# | −0.44 |
|
Ergosterol biosynthesis | | | | | | | |
orf19.1631* | ERG6
*
| Delta(24)-sterol C-methyltransferase* | −0.67 | 0.20 | −3.61# | −2.84 | −6.05# | −4.09# | −1.34 |
orf19.2016* | | Possible role in ergosterol biosynthesis* | −2.26 | 0.16 | 2.13 | −3.22# | −3.69# | −3.14# | 1.05 |
orf19.922* | ERG11
*
| Lanosterol 14-alpha-demethylase* | −1.29 | −0.44 | −0.73 | −5.19# | −4.14# | −5.50# | −2.26 |
|
Filamentous growth | | | | | | | |
orf19.815 | DCK1 | Putative guanine nucleotide exchange factor required for embedded filamentous growth | −1.76 | −4.90# | −0.07 | 0.47 | −4.22# | −1.11 | −4.89# |
orf19.3669 | SHA3 | Putative serine/threonine kinase | −1.04 | −2.35 | −0.77 | −3.24# | −3.27# | −1.55 | −3.89# |
orf19.3575* | CDC19
*
| Putative pyruvate kinase; mutation affects filamentation* | −2.04 | −0.07 | 0.20 | −3.09# | −3.12# | −3.97# | 0.49 |
|
Gluconeogenesis | | | | | | | |
orf19.7514* | PCK1* | Phosphoenolpyruvate carboxykinase* | −0.22 | −3.90# | 2.82 | 1.21 | −3.89# | −3.66# | −2.91 |
|
Glutathione biosynthetic process | | | | | | | |
orf19.5059 | GCS1 | Gamma-glutamylcysteine synthetase | −2.60 | −3.06# | −3.10# | 1.00 | −2.27 | −0.52 | −3.85# |
|
Intracellular transport | | | | | | | |
orf19.4805 | | Putative membrane protein | −1.19 | 1.35 | −0.56 | −3.69# | −3.87# | −3.64# | −2.47 |
|
Lipoate biosynthetic process | | | | | | | |
orf19.819 | | Possible role in lipoate biosynthesis | −1.06 | −3.54# | 1.91 | 0.27 | −4.15# | −3.69# | −0.94 |
|
NAD biosynthetic process | | | | | | | |
orf19.1460 | | Putative glutamine-dependent NAD synthetase | −2.41 | −2.49 | 0.05 | −0.79 | −3.60# | −3.23# | −3.51# |
|
Oxidation/Reduction | | | | | | | |
orf19.5517 | | Similar to alcohol dehydrogenases | −2.94 | −0.19 | −0.85 | −4.83# | −6.56# | −8.21# | −0.07 |
orf19.2525 | LYS12 | Mitochondrial homoisocitrate dehydrogenase | −2.17 | 1.04 | −1.19 | −5.01# | −5.72# | −7.22# | 0.65 |
|
RNA processing | | | | | | | |
orf19.7215 | | Ortholog(s) have snoRNA binding activity | −2.83 | −0.06 | −0.38 | −0.16 | −5.20# | −4.12# | −3.23# |
orf19.3159 | UTP20 | Similar to S. cerevisiae nucleolar protein Utp10p | −1.27 | −0.48 | −0.20 | −2.29 | −5.60# | −3.26# | −3.15# |
|
Signaling | | | | | | | |
orf19.3453 | | Possible role in signal transduction | −1.58 | −0.21 | 0.89 | −4.27# | −3.25# | −4.07# | 0.09 |
orf19.6906* | ASC1
*
| Protein described as part of 40S ribosomal subunit* | −3.30# | −2.92 | −1.91 | 0.37 | −3.74# | −4.70# | −2.62 |
|
TCA cycle | | | | | | | |
orf19.6632 | ACO2 | Aconitate hydratase 2 | −1.14 | −0.25 | 0.55 | −3.34# | −6.53# | −4.39# | 0.05 |
|
Translation | | | | | | | |
orf19.6253* | RPS23A
*
| Putative ribosomal protein* | −1.19 | −3.68# | −0.63 | −3.51# | −2.82 | −2.86 | −3.17# |
orf19.4152* | CEF3
*
| Translation elongation factor 3* | −2.13 | −3.35# | 0.54 | 0.12 | −3.18# | −1.03 | −3.86# |
|
Transport | | | | | | | |
orf19.4599 | PHO89 | Putative phosphate permease | 0.73 | −0.06 | −2.63 | −11.05# | −6.49# | −5.80# | −6.50# |
orf19.5170 | ENA21 | Possible sodium transporter sodium transporters | −0.77 | −2.46 | −1.35 | −3.59# | −4.30# | −5.16# | −1.38 |
orf19.6000* | CDR1
*
| ABC transporter involved in multidrug resistance* | −0.09 | −0.21 | −2.97 | −1.76 | −5.00# | −5.04# | −3.82# |
|
Unknown | | | | | | | |
orf19.7413 | | MMS21-SMC5-SMC6 complex component | −3.01# | −3.22# | 1.62 | −3.10# | −1.53 | −1.75 | 0.55 |
orf19.1549 | | Unknown | −0.42 | −1.89 | −3.17# | −3.96# | −3.83# | −2.95 | −1.10 |
orf19.4651 | PGA53 | Putative GPI-anchored protein | −0.84 | −1.33 | −1.16 | −3.73# | −3.33# | −3.75# | 0.35 |
orf19.5799 | | Unknown | 0.24 | −0.13 | −1.23 | −3.54# | −4.95# | −5.27# | −1.11 |
orf19.915 | | Unknown | −0.56 | 1.05 | −0.59 | 0.19 | −3.60# | −3.15# | −3.21# |
orf19.5760 | IHD1 | Putative GPI-anchored protein | −2.64 | −5.84# | −0.54 | −5.21# | −3.27# | −5.36# | −5.36# |
orf19.3548 | | Unknown | −3.48# | −1.88 | −0.44 | 1.89 | −3.13# | −3.08# | −0.96 |
|