Clinical Study

Consistency of Mycobacterium tuberculosis-Specific Interferon-Gamma Responses in HIV-1-Infected Women during Pregnancy and Postpartum

Table 2

(a) Odds of consistently positive interferon-γ release assays in women associated with baseline magnitude of interferon-γ response >8 compared to ≤8 SFCs/well. (b) Odds of >50% postpartum visits with positive interferon-γ release assays in women with baseline magnitude of interferon-γ response >8 compared to ≤8 SFCs/well.
(a)

Postpartum consistency of IGRAs
Interferon-γ response* (SFCs/well) during pregnancyYesNoOdds ratio (95% confidence interval); value

>88410.0 (0.85–117.0); 0.07
≤815

(b)

Greater than 50% postpartum visits with positive IGRAs
Interferon-γ response* (SFCs/well) during pregnancy Yes NoOdds ratio (95% confidence interval); value

>8 10 25.0 (0.55–45.39); 0.15
≤8 3 3

Note: IGRA interferon-gamma release assay.
*Maximum of ESAT-6/CPF-10 minus negative control.