Candida Chorioamnionitis Leads to Preterm Birth and Adverse Fetal-Neonatal Outcome

Table 5

Antenatal treatment for Candida chorioamnionitis.

GA at diagnosis (weeks)	GA at delivery (weeks)	Species	Antifungal agent	Administration route	Fetal/neonatal outcomes	Reference
19	19	Candida albicans	Fluconazole	Intravenous	Stillbirth	[74]
19	21	C. albicans	Fluconazole	Oral	Stillbirth	[75]
21	22	C. albicans	Fluconazole	Oral	Stillbirth	[64]
21	27	C. albicans	Fluconazole	Transabdominal intra-amniotic, oral, and vaginal	Alive	[71]
23	31	C. albicans	Fluconazole	Transabdominal intra-amniotic, oral, and vaginal	Alive	[71]
26	29	C. glabrata	Fluconazole	Intravenous	Alive (PVL)/alive	[81]
18	23	C. glabrata	Amphotericin B	Intravenous	Stillbirth	[88]
21	24	C. glabrata	Amphotericin B	Intravenous	Stillbirth/stillbirth	[87]
24	24	C. glabrata	Amphotericin B	Intravenous	Died on day 42	[76]
24	28	C. glabrata	Amphotericin B	Intravenous	Alive/alive	[89]
27	29	C. albicans	Amphotericin B	Transcervical intra-amniotic	Alive	[44]
21	21	C. albicans	Ketoconazole	Not described	Stillbirth	[91]
26	28	C. glabrata	Micafungin	Intravenous	Alive	[41]

GA, gestational age; PVL, periventricular leukomalacia.