HIV and Reproduction: Fertility, Contraception, and Preconception Issues and Interventions
1Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
2Department of Obstetrics and Gynecology, University of California at San Francisco, San Francisco, CA, USA
3Department of Obstetrics and Gynecology, Brown University, Providence, RI 02906, USA
HIV and Reproduction: Fertility, Contraception, and Preconception Issues and Interventions
Description
There has been a 150% increase in live births to HIV-infected women in the era of effective combination antiretroviral therapy, related to advances both in treatment of HIV and prevention of perinatal transmission. Although a substantial number of HIV-infected individuals express the intention to have children, unintended pregnancy rates remain high and there continue to be outstanding questions regarding the safety of contraceptive methods, particularly hormonal contraceptives, in the setting of HIV. Newer developments in biomedical prevention, including preexposure prophylaxis (PrEP), offer new opportunities for safe conception with HIV serodiscordant couples.
We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the effects of HIV on fertility, the contraceptive considerations in HIV-infected women, interventions for safer conception, and the evaluation of pregnancy and other fertility outcomes in both resource-rich and resource-limited settings. Potential topics include, but are not limited to:
- Effects of hormonal contraception on HIV transmission and progression
- Use of alternative, including long-acting, hormonal contraceptive methods in HIV-infected women
- Characterization of HIV-serodiscordant relationships and their pregnancy intentions
- Important preconception interventions in HIV concordant and discordant couples, including safe conception
- Feasibility and acceptability of biomedical interventions to prevent sexual transmission in serodiscordant couples
- Pregnancy outcomes in HIV-infected women
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