Kinetic Spectrophotometric Determination of Certain Cephalosporins in Pharmaceutical Formulations

Table 6

Evaluation of precision of the initial rate and fixed time methods of the proposed kinetic spectrophotometric method for determination of investigated cephalosporins.

Drug	Amount taken	Recovery (%±SD)
	(𝜇g mL^-1)	Initial rate method	Fixed time method
Cefotaxime	5	100.1 ± 1.072	99.82 ± 0.7246
	9	99.88 ± 0.6859	100.9 ± 0.7086
	15	99.95 ± 0.5668	100.6 ± 0.6286
Cephapirin	5	100.16 ± 1.015	100.29 ± 1.144
	9	99.68 ± 0.6840	99.2 ± 0.7160
	15	100.31 ± 0.7624	100.44 ± 0.6225
Cephradine	5	100.61 ± 0.8049	100.53 ± 1.125
	9	99.94 ± 0.5594	101.84 ± 0.9913
	15	99.70 ± 0.6116	100.51 ± 0.9054
Cephalexin	5	99.56 ± 0.7435	98.64 ± 0.7306
	9	99.78 ± 0.5811	100.04 ± 0.4796
	15	99.76 ± 0.4575	100.78 ± 0.6091
Ceftazidime	5	100.2 ± 1.002	99.53 ± 1.309
	9	100.19 ± 0.7958	100.6 ± 0.9820
	15	99.43 ± 0.8901	99.88 ± 0.6205
Cefazoline	5	99.88 ± 1.066	99.64 ± 1.082
	9	101.07 ± 0.8312	101.45 ± 0.4871
	15	100.44 ± 0.7346	99.46 ± 0.5538
Ceftriaxone	5	99.28 ± 1.154	99.34 ± 0.9175
	9	99.99 ± 0.8687	100.54 ± 0.8347
	15	100.76 ± 0.6403	99.98 ± 0.4933
Cefuroxime	5	100.19 ± 1.19	99.52 ± 0.8834
	9	100.4 ± 0.8276	99.23 ± 0.9490
	15	100.39 ± 0.6692	100.94 ± 0.408