Spectrophotometric Determination of N-Acetyl-L-Cysteine and N-(2-Mercaptopropionyl)-Glycine in Pharmaceutical Preparations

Table 2

Determination of NAC and MPG in their pharmaceutical formulations by the proposed spectrophotometric equilibrium method and by a literature method [24].

Pharmaceutical preparation	Present work^(a) mg	Method from [24] ^(a) mg
Fluimukan^(b) (NAC)	202.0 ± 1.9	202.9 ± 3.2
Fluimukan Akut^(c) (NAC)	605.9 ± 6.1	606.9 ± 7.2
Captimer^(d)(MPG)	99.2 ± 0.8	99.0 ± 1.0

^(a)Average of three determinations ± SD.
^(b)Granules containing 200 mg NAC and excipients.
^(c)Dispersible tablets containing 600 mg NAC and excipients.
^(d)Tablets containing 100 mg MPG and excipients.