Research Article
Utility of N-Bromosuccinimide for the Titrimetric and Spectrophotometric Determination of Famotidine in Pharmaceutical Formulations
Table 4
Recovery of the drug from synthetic mixture.
| Method | FMT in synthetic mixture taken | FMT recovered (percent ± SD) |
| Method A | 2.0 | 105.4 ± 1.13 | | 5.0 | 99.17 ± 1.21 | | 9.0 | 96.54 ± 1.08 | Method B | 2.0 | 96.01 ± 1.14 | | 4.0 | 95.93 ± 1.26 | | 6.0 | 94.78 ± 1.46 | Method C | 3.0 | 101.0 ± 1.04 | | 4.5 | 100.8 ± 1.01 | | 6.0 | 96.82 ± 0.98 | Method D | 0.6 | 117.3 ± 1.19 | | 1.8 | 122.1 ± 1.05 | | 3.0 | 113.7 ± 1.15 |
|
|
mg in titrimetry and g mL−1 in spectrophotometry. Mean value of five determinations.
|