Research Article

Sensitive and Selective Spectrophotometric Determination of Gabapentin in Capsules Using Two Nitrophenols as Chromogenic Agents

Table 6

Results of assay of capsules and statistical evaluation.

Capsule brand nameFound (% of nominal amount ± SD)*
Reference methodProposed methods
Method AMethod B

Gabantin-10099.32 ± 1.0498.27 ± 1.97
t = 1.05
F = 3.59
97.01 ± 2.24
t = 2.09
F = 4.64

Gabapin-30098.07 ± 1.3799.13 ± 1.88
t = 1.02
F = 1.88
98.96 ± 2.11
t = 0.79
F = 2.37

*Mean value of five determinations.
Tabulated t-value at the 95% confidence level is 2.78.
Tabulated F-value at the 95% confidence level is 6.39.