Application of Certain π-Acceptors for the Spectrophotometric Determination of Alendronate Sodium in Pharmaceutical Bulk and Dosage Forms

Table 3

Determination of alendronate sodium in pharmaceutical formulations by the proposed and reference [23] methods.

Sample	Recovery ± S.D.
	Official method	Method A	Method B
Fosamax tablets	99.60 ± 0.83	99.75 ± 0.78	99.87 ± 0.69
𝑡		0.24	0.60
𝐹		1.15	1.14
Ostepor tablets	100.02 ± 0.46	99.56 ± 0.53	99.92 ± 0.53
𝑡		1.24	0.54
𝐹		1.58	1.28
Bongard tablets	99.75 ± 0.63	99.90 ± 0.41	100.05 ± 0.61
𝑡		1.42	0.52
𝐹		0.75	1.13
Bonate tablets	100.12 ± 0.52	100.01 ± 0.57	99.89 ± 0.68
𝑡		1.28	0.34
𝐹		1.22	1.12

*Average of 3 independent analyses.