Low-Level Detection of Poly(amidoamine) PAMAM Dendrimers Using Immunoimaging Scanning Probe Microscopy

Figure 4

SPM image of capture surface patterning: (a) height and (b) phase (8 × 8 μm), zoomed in analysis; (c) height and (b) phase of capture stripe (avidin immobilized on DSP) containing bound G4 biotinylated PAMAM dendrimers. Cross-section analysis of bound G4 biotinylated PAMAM dendrimers in (d) is shown in (e). The capture platform was exposed to 200 μL of 5.0 μmol/L concentration of G4 biotinylated PAMAM dendrimer solution.

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