Live Cells as Dynamic Laboratories: Time Lapse Raman Spectral Microscopy of Nanoparticles with Both IgE Targeting and pH-Sensing Functions

Figure 3

Normalized and offset Raman spectra during in vitro sensor development. (A) Raman spectrum of Au@Ag colloids. (B) Raman spectrum of 4-MPy adherent to Au@Ag colloids. (C) Raman spectrum of DNP adherent to Au@Ag colloids. (D) Raman spectrum of targeted nanosensor with DNP and 4-MPy ligands. 𝑌  axis is arbitrary intensity units. Reprinted with permission from Nowak-Lovato et al. [11] (copyright 2009 Society for Applied Spectroscopy).