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Figure 3: Normalized and offset Raman spectra during in vitro sensor development. (A) Raman spectrum of Au@Ag colloids. (B) Raman spectrum of 4-MPy adherent to Au@Ag colloids. (C) Raman spectrum of DNP adherent to Au@Ag colloids. (D) Raman spectrum of targeted nanosensor with DNP and 4-MPy ligands.   axis is arbitrary intensity units. Reprinted with permission from Nowak-Lovato et al. [11] (copyright 2009 Society for Applied Spectroscopy).