Review Article

Live Cells as Dynamic Laboratories: Time Lapse Raman Spectral Microscopy of Nanoparticles with Both IgE Targeting and pH-Sensing Functions

Figure 5

Time-lapse pH-calibrated images acquired every 3.5 min upon nanosensor addition up to 90 min. Calibrated pixels demonstrating pH are overlaid with bright field images. (a) 28 minutes, (b) 45.5 minutes, (c) 59.5 minutes and (d) 80.5 minutes. Reprinted with permission from Nowak-Lovato et al. [11] (copyright 2009 Society for Applied Spectroscopy).
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(a)
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(b)
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(c)
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(d)