Liquid Chromatography/Tandem Mass Spectrometry Method for Quantitation of Cremophor EL and Its Applications

Figure 1

Components of CrEL according to [3]; hydrophobic portion consisting of (a) glycerol polyoxyethylene ricinoleate esters (R1, R2 corresponds to ricinoleic acid). (b) polyoxyethylene ricinoleate esters; hydrophilic portion consisting of (c) glycerol polyoxyethylene ether (d) free polyethyleneglycol.