Liquid Chromatography/Tandem Mass Spectrometry Method for Quantitation of Cremophor EL and Its Applications
Figure 4
(a) Parent ion scan representing the molecular ions of hydrophobic oligomers (glycerol polyoxyethylene ricinoleate) of CrEL (b) Fragmentation pattern of selected oligomer with m/z 932.50. (c) Remaining percent versus time curve representing the plasma stability of hydrophilic and hydrophobic components of CrEL.