Two Validated Spectrofluorometric Methods for Determination of Gemifloxacin Mesylate in Tablets and Human Plasma

Table 4

Determination of GFX in its pharmaceutical dosage forms using the proposed methods.

Dosage form	Recovery % ± SD (𝑛=4)
	Micelle-enhanced spectrofluorometric method	Hantzsch reaction method	Reported method^a
	99.78±0.88	99.44±0.81	100.09±0.50
Factive	𝑡=0.61^b	𝑡=1.35^b
	𝐹=3.17^b	𝐹=2.69^b
	99.07±0.66	100.85±0.56	100.14±1.05
Simulated tablets contain Ambroxol HCl	𝑡=1.72^b	𝑡=1.19^b
	𝐹=2.49^b	𝐹=3.49^b

aReference [9].
bTheoretical value for 𝑡 and 𝐹 at 95% confidence limit, 𝑡=2.45 and 𝐹=9.23.