Two Validated Spectrofluorometric Methods for Determination of Gemifloxacin Mesylate in Tablets and Human Plasma

Table 5

Determination of GFX in spiked human plasma samples using the proposed methods.

Method	Spiked amount; (ng/mL)	Found (ng/mL)	Recovery % ± SD^a
	20	19.52	97.60±0.92
Micelle-enhanced spectrofluorometric	125	123.98	99.18±1.23
	500	495.50	99.10±0.69
	250	248.11	99.25±0.97
Hantzsch reaction	500	498.25	99.65±1.42
	1000	1007.07	100.71±0.88

aMean of five determinations.