Utilization of N-Bromosuccinimide as a Brominating Agent for the Determination of Sumatriptan Succinate in Bulk Drug and Tablets

Table 5

Results of analysis of tablets by the proposed methods.

Tablet brand name	Label claim; mg/tablet	Found (percent of label claim ± SD)^a
		Reference method	Proposed methods
			Method A	Method B	Method C
Suminat-25	25	101.1 ± 0.83	99.52±1.19	101.6±1.45	101.8±1.20
			𝑡=2.44	𝑡=0.67	𝑡=1.07
			𝐹=2.06	𝐹=3.05	𝐹=2.09
Suminat-50	50	99.43 ± 1.05	100.9±0.81	101.2±1.77	99.09±1.83
			𝑡=2.48	𝑡=1.92	𝑡=0.36
			𝐹=0.60	𝐹=2.84	𝐹=3.04

aMean value of five determinations.
Tabulated 𝑡-value at the 95% confidence level is 2.78.
Tabulated 𝐹-value at the 95% confidence level is 6.39.