Micellar Enhanced Spectrofluorimetric Method for the Determination of Ponatinib in Human Plasma and Urine via Cremophor RH 40 as Sensing Agent

Table 4

Robustness results of the proposed analytical procedure.

Variation of the experimental parameters	% Recovery ± SD
No change	99.68 ± 0.88
Cr RH 40 volume (µL)
580	101.98 ± 0.39
620	101.83 ± 1.16
pH
7.8	101.76 ± 0.84
8.2	103.00 ± 0.35
Buffer volume (µL)
0.95	102.37 ± 0.98
1.05	102.59 ± 1.12
Temperature (°C)
20	102.61 ± 0.35
30	99.68 ± 1.17

Average of triplicate measurements.
According to the general calibration procedures.