Development and Validation of Simple RP-HPLC Method for Intracellular Determination of Fluconazole Concentration and Its Application to the Study of<i> Candida albicans</i> Azole Resistance

<div>Typical chromatogram of IS and FLC (250 ng/mL) from extracted samples of blank<i> C. albicans</i> (a). Chromatographic separation of IS and FLC in<i> C. albicans</i> ATCC-10231 samples long-term cultivated in the presence of FLC.</div>

International Journal of Analytical Chemistry

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Figure 2

Figure 2: Development and Validation of Simple RP-HPLC Method for Intracellular Determination of Fluconazole Concentration and Its Application to the Study of<i> Candida albicans</i> Azole Resistance 

Figure 2 | Development and Validation of Simple RP-HPLC Method for Intracellular Determination of Fluconazole Concentration and Its Application to the Study of Candida albicans Azole Resistance 