Stability-Indicating HPLC Determination of Gemcitabine in Pharmaceutical Formulations

Figure 6

Typical HPLC chromatogram of (a) gemcitabine exposed to acidic stress (1 N HCl, 60°C, 1 h), (b) contour plot, (c) peak purity index, and extracted UV spectrum of (d) degraded product d-5, (e) d-7, and (f) d-8.

(a)

(b)

(c)

(d)

(e)

(f)