Research Article
Stability-Indicating HPLC Determination of Gemcitabine in Pharmaceutical Formulations
Table 1
Linearity data of the proposed method.
| Conc. (µg/mL) | Mean peak area (gemcitabine) () | Mean peak area (IS) | Mean area ratio | Conc. found (µg/mL) | % assay |
| 0.5 | 11556.2 | 490138.6 | 0.02358 | 0.50 | 99.0 | 1.0 | 22196.2 | 527242.0 | 0.04210 | 1.03 | 102.6 | 2.0 | 40119.6 | 516202.8 | 0.07772 | 2.05 | 102.3 | 5.0 | 99206.8 | 549256.6 | 0.18062 | 4.99 | 99.9 | 10.0 | 197702.2 | 546987.8 | 0.36144 | 10.18 | 101.8 | 15.0 | 298096.4 | 551610.8 | 0.54041 | 15.30 | 102.0 | 25.0 | 496084.0 | 560316.6 | 0.88536 | 25.19 | 100.8 | 40.0 | 791722.0 | 566686.4 | 1.39711 | 39.85 | 99.6 | 50.0 | 987580.6 | 553478.0 | 1.78432 | 50.95 | 101.9 | , |
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