Development and Validation of HPLC Method for the Simultaneous Determination of Five Food Additives and Caffeine in Soft Drinks

Table 1

The experimental variables and levels of BBD.

Variable	Level
	−1	0	+1
pH ()	6.0	6.5	7.0
Flow rate () (mL min^−1)	1.0	1.2	1.4
Mobile phase ratio () (%)	85	90	95