Research Article
Development and Validation of HPLC Method for the Simultaneous Determination of Five Food Additives and Caffeine in Soft Drinks
Table 2
Experimental design matrix and the responses for BBD.
| Run | | | | |
| 1 | 6.0 | 1.0 | 90 | 1.041 | 2 | 7.0 | 1.0 | 90 | 0.622 | 3 | 6.0 | 1.4 | 90 | 0.553 | 4 | 7.0 | 1.4 | 90 | 0.128 | 5 | 6.0 | 1.2 | 85 | 0.000 | 6 | 7.0 | 1.2 | 85 | 0.027 | 7 | 6.0 | 1.2 | 95 | 3175.373 | 8 | 7.0 | 1.2 | 95 | 1792.207 | 9 | 6.5 | 1.0 | 85 | 0.046 | 10 | 6.5 | 1.4 | 85 | 0.000 | 11 | 6.5 | 1.0 | 95 | 2487.823 | 12 | 6.5 | 1.4 | 95 | 1257.455 | 13 | 6.5 | 1.2 | 90 | 0.759 | 14 | 6.5 | 1.2 | 90 | 0.327 | 15 | 6.5 | 1.2 | 90 | 0.918 |
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