Selective Sensing of Tyrosine Phosphorylation in Peptides Using Terbium(III) Complexes

Figure 2

Mechanism of selective detection of enzymatic phosphorylation of Tyr by complex. The photoexcited energy (Ex) absorbed by the benzene ring (antenna) is transferred to the (ET), resulting in enormous promotion of the intensity of luminescence emitted from this metal ion (Em). Accordingly, the emission is evident only for pTyr which fulfills both of the two requirements for the mechanism (notable antenna effect and sufficient binding activity towards the ).