Selective Sensing of Tyrosine Phosphorylation in Peptides Using Terbium(III) Complexes

Table 1

IC₅₀ of PTK inhibitors.

IC50 (nM)	Dasatinib	Gefitinib	Imatinib	Staurosporine
Src	12 ± 0.96	>5000	—	310 ± 28
Fyn	26 ± 2.2	>2000	>10000	260 ± 19
EGFR	1400 ± 110	22 ± 2.4	—	2300 ± 820

Not determined due to poor curve fitting of weak inhibitors. Inhibition was not observed.