Rapid Determination of Isomeric Benzoylpaeoniflorin and Benzoylalbiflorin in Rat Plasma by LC-MS/MS Method

Table 4

BP and BA stability in QC samples ().

Compound	Concentration/ng mL^−1	Three freeze thaw cycles			Short-term for 4 h (25°C)			Long-term for 30 Days (25°C)
		Mean ± SD	RSD, %	RE, %	Mean ± SD	RSD, %	RE, %	Mean ± SD	RSD, %	RE, %
BP	1	0.99 ± 0.03	3.77	0.16	0.91 ± 0.05	5.60	9.00	0.88 ± 0.09	10.99	11.50
	2	2.04 ± 0.18	9.14	−2.00	1.85 ± 0.07	3.91	7.33	1.81 ± 0.08	4.79	9.50
	400	382.33 ± 32.20	8.42	4.41	397.50 ± 9.18	2.30	0.62	382.66 ± 11.86	3.09	4.33
	750	747.50 ± 9.87	1.32	0.33	743.00 ± 15.15	2.03	0.93	740.50 ± 4.18	0.56	1.26
BA	1	0.94 ± 0.06	6.38	6.00	0.93 ± 0.03	3.90	7.00	0.91 ± 0.04	4.86	9.00
	2	1.96 ± 0.10	5.27	1.91	2.00 ± 0.07	3.69	−0.41	2.19 ± 0.18	8.24	−9.83
	400	404 ± 8.09	2.00	−1.00	397.66 ± 16.04	4.03	0.58	396.83 ± 16.19	4.08	0.79
	750	746 ± 5.17	0.69	0.53	755.83 ± 13.99	1.85	−0.77	757.66 ± 17.71	2.33	−1.02