Quantitative Analysis of Favipiravir by HPLC: Development and Validation

Table 8

Ruggedness results.

Sa. #		Area of standard	% assay
			Area of sample	%
Analyst 1	1	36.877	36.941	100.1%
	2	36.967	36.133	97.9%
	3	36.958	36.779	99.7%
	4	36.884	36.963	100.2%
	5	36.952	36.999	100.3%
	6	36.788	37.009	100.3%
	Avg	36.9	36.804	99.7%
	RSD	0.2%	0.9%	0.9%
Analyst 2	1	36.407	36.679	98.6%
	2	36.491	36.292	97.6%
	3	36.390	37.384	100.5%
	4	36.512	35.963	96.7%
	5	36.432	36.680	98.6%
	6	36.479	35.743	96.1%
	Avg	36.5	36.457	98.0%
	RSD	0.1%	1.6%	1.6%
	Absolute difference	—	—	1.5%
	RSD (all)			For both analysts