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Detection methods | Advantages | Disadvantages |
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GC-MS/MS | Good sensitivity, accuracy and precision, high analysis efficiency, and wide application range | Unsuitable for analysis of compounds that are strongly polar, nonvolatile, or thermally unstable; expensive instrumentation |
LC-MS/MS | Wide analysis range; able to analyze compounds that GC-MS/MS cannot | Complicated, cumbersome, and expensive instrumentation |
TLC | Rapid detection and low cost; simple and portable instrumentation; strong selectivity | Low sensitivity and poor separation ability |
UV-Vis | High sensitivity, simple operation; can simultaneously analyze multiple compounds | Potential for spectral interference caused by overlapping spectral lines; relatively low selectivity |
NIR | Wide application range, can provide structural information | Not suitable for analyzing water-containing samples; data analysis is complex |
THz | Rapid and nondestructive detection | Instrumentation is cumbersome and expensive; low detection sensitivity |
Raman | Rapid detection, simple and portable instrumentation; provides “fingerprints” of target substances | Weak spectral signal; poor sensitivity and precision |
SERS | Fast detection; portable instrumentation with simple operation; high sensitivity | Easily disturbed by external factors; low stability of quantitative calculation models |
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