Brain Imaging of Nicotinic Receptors in Alzheimer's Disease

<table>Comparison with regional uptake values of 5-[<sup>123</sup>I]I-A85380 in age-matched healthy control and patients with Alzheimer’s disease. Significant bilateral reductions in nicotinic receptor binding were identified in frontal, striatal, right medial temporal, and pons in patients with AD compared to controls. (Data is from the paper of O'Brien et al. [<a href="/journals/ijad/2010/548913/#B59">59</a>].) <svg height="13.95" id="M5" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.162498 13.95" width="58.162498" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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International Journal of Alzheimer’s Disease

Brain Imaging of Nicotinic Receptors in Alzheimer's Disease

Figure 3