Modeling of Tau-Mediated Synaptic and Neuronal Degeneration in Alzheimer's Disease

Figure 1

Expression of EGFP following hippocampal injection of AAV1/2.EGFP is long-lasting. Six months following intracerebral injection of the AAV.EGFP vector, the transgene remained expressed in the CA1/2 subfields of the hippocampus and in the deeper layers of the cortex. Expression of EGFP is also evident in and likely propagates along axonal projections of the fornix.