Research Article
Predictors of the Progression of Dementia Severity in Brazilian Patients with Alzheimer's Disease and Vascular Dementia
Table 1
Demographic and clinical data at study entry.
| | Variable | Alzheimer () | Vascular () |
| | Age (in years) meanSD (range) | 73.23 7.72 (60–87) | 67.41 9.08 (50–86) |
| | Sex | | | | Male | 11 (32%) | 28 (61%) | | Female | 23 (68%) | 18 (39%) |
| | Educational Attainment (in years) meanSD (range) | 4.30 3.99 (0–16) | 4.76 4.06 (0–16) |
| | Vascular risk factors | | | | None | 28 (82%) | — | | Hypertension | 04 (12%) | 33 (72%) | | DM | 02 (6%) | 04 (9%) | | Hypertension + DM | 00 (0%) | 09 (20%) |
| | Family history | | | | No | 18 (53%) | 24 (52%) | | Yes | 11 (32%) | 08 (17%) | | Uncertain | 05 (15%) | 14 (30%) |
| | Duration of follow-up (in months) mean SD (range) | 11.016.19 (3–25) | 11 6.31 (3–27) |
| | Neurological Examination | | | | Normal | 34 (100%) | | | Neurological sign (hemiparesis, lower facial | | | | weakness, Babinski sign, sensory deficit, | — | 25 (59%) | | hemianopia, and dysarthria)* | | | | Other discrete symptoms- | | 19 (41%) | | (mild asymmetric deep tendon reflex, tremor) | |
| | Hachinski ischemic score mean SD (range) | 2.90 0.6 (1–4) | 9.13 2.61 (5–19) |
| | CT scans: | | | | Normal | 19 (56%) | — | | Mild diffuse atrophy AND/OR ventricles | 15 (44%) | — | | Atrophy leukoaraiosis | — | 12 (26%) | | Focal abnormality | — | 34 (74%) |
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DM: Diabetes Mellitus; *NINDS-AIREN suggested symptoms.
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