Predictors of the Progression of Dementia Severity in Brazilian Patients with Alzheimer's Disease and Vascular Dementia

Table 2

Predictive factors in Cox Proportionate Hazards Models, including diagnosis of dementia, age, educational level, sex, family history of dementia, and CT scan findings, for the progression of dementia (worsening of severity according to CDR scale).

Variable	Hazards ratio	CI 95% lower–upper	𝑃-value	𝑟
Diagnosis of dementia	0.949	0.30–3.05	.939	−0.053
Age	1.049	0.96–1.15	.318	0.048
Sex	0.433	11–1.70	.230	−0.838
Educational level	1.185	1.02–1.37	.024	0.170
Family history of dementia			.785
Present	0.983	0.24–4.08	.982	−0.017
Unknown	0.559	0.11–2.89	.487	−0.581
CT findings			.881
Mild diffuse atrophy AND/OR ↑ventricles	15831.99	0.00–6.2𝐸^+096	.929	9.670
Atrophy + leukoaraiosis	34834.69	0.00–1.4𝐸^+097	.923	10.458
Focal abnormality	16949.11	0.00–6.6𝐸^+096	.929	9.738

Diagnosis of dementia: 0 = VaD; 1 = AD.