Review Article

The Pathological Roles of Ganglioside Metabolism in Alzheimer's Disease: Effects of Gangliosides on Neurogenesis

Figure 2

The content of Chol-1α antigens, GT1aα (a) and GQ1bα (b), in AD model mouse brains [85]. GT1aα and GQ1bα extracted from brains of AD model double transgenic mice coexpressing mouse/human chimeric APP with the Swedish mutation and human presenilin-1 with a deletion of exon 9 (Tg) or age-matched wild-type mice (WT) were quantified by densitometric analysis of high-performance thin-layer chromatography immunostaining. . (Reproduced from [85] with permission).
193618.fig.002a
(a) GT1aα
193618.fig.002b
(b) GQ1bα