Membrane Incorporation, Channel Formation, and Disruption of Calcium Homeostasis by Alzheimer's β-Amyloid Protein
Figure 4
AFM images of AβP(1–40) on monolayer membranes. Lipid monolayer membranes composed by DPPC (a) or ganglioside GM1-DPPC (dipalmitoil phosphatidyl choline) (b)~(d) were prepared by bath sonication and reconstitution on mica plates. The ratio of GM1:DPPC was 8 : 2. AFM images were obtained after the exposure to freshly prepared AβP(1–40) (c) or aged AβP(1–40) (d). Scale area: 1.5 × 1.5 μm.
