A Novel Study and Meta-Analysis of the Genetic Variation of the Serotonin Transporter Promoter in the Italian Population Do Not Support a Large Effect on Alzheimer's Disease Risk

Table 2

Demographics of the AD sample.

Diagnosis	No. of subjects (male : female)	Age at sampling (years ± SD)	Age at onset (years ± SD)	Disease duration (years ± SD)	MMSE score at sampling (mean ± SD)
AD	235 (74 : 161)	78.6±9.8	77.2±8.0	4.1±1.8	18.7±5.8
CNTR	207 (69 : 138)	77.0±9.3	NA	NA	28.2±2.6 **

AD: sporadic Alzheimer’s disease;
CNTR: controls;
MMSE: Minimental State Examination;
SD: standard deviation;
NA: not applicable;
** 𝑃<.001, Student’s 𝑡-test versus AD.