Research Article
Association Study of Genetic Variants in CDKN2A/CDKN2B Genes/Loci with Late-Onset Alzheimer's Disease
Table 1
Main characteristics of all studied subjects.
| | Characteristics | LOADa | Controls |
| | Total | 238 | 250 | | Gender, no. (%) | | | | Female | 152 (63.9) | 156 (62.4) | | Male | 86 (36.1) | 94 (38.6) | | Recruitment site, no. (%) | | | | Italy | 218 (91.6) | 230 (92) | | Germany | 20 (8.4) | 20 (8) | | Age at onsetb, mean (±SD) | 72.9 (±5.6) | 71.5 (±5.7) | | MMSE points, mean (±SD) | 20.2 (±5.4) | 28.2 (±1.4) | | APOEε4, no. (%) | | | | No | 133 (55.9) | 221 (88.4) | | Yes | 105 (44.1) | 29 (11.6) |
|
|
aLOAD cases were defined by the occurrence of Alzheimer’s disease with an onset age ≥65 years.
bAt examination tests for controls.
|
