E22Δ Mutation in Amyloid β-Protein Promotes β-Sheet Transformation, Radical Production, and Synaptotoxicity, But Not Neurotoxicity
Figure 2
CD spectra of E22Δ-Aβ40 and E22Δ-Aβ42 (25 μM). (a) Aβ40, (b) E22Δ-Aβ40, (c) Aβ42, (d) E22Δ-Aβ42. Each Aβ (25 μM) was incubated in phosphate buffer at 37°C for the following times: □, 0 h; ▲, 4 h; △, 8 h; °, 24 h; ■, 48 h.
