MRI Shows More Severe Hippocampal Atrophy and Shape Deformation in Hippocampal Sclerosis Than in Alzheimer's Disease
Figure 1
Hippocampal surface deformities in AD (a) and HS (b) compared to NC. Right and left hippocampi are viewed from the top (dorsal surface, left panel) or the bottom (ventral surface, right panel). The flame scale (b) represents the difference between the mean surface of the disease hippocampus and the mean surface of NC hippocampus. Inward deformations are represented by cooler colors (blue to purple), while outward deformations are represented by warmer colors (orange to red). Green to yellow represent near zero deformations. Maximum deformation is 2 mm in either direction. The lateral surface (labeled CA1) is proximal to CA1, where the greatest deformations are found. Labels: SUB = subiculum, CA2-4, DG = combined fields of CA2, CA3, CA4, and the dentate granule cell layer.
