The Cellular Prion Protein Prevents Copper-Induced Inhibition of P2X4 Receptors

Figure 1

Coexpression of P2X₄ and PrP^C in X. laevis oocytes. (a) Western blot of total lysate fractions from a non-injected oocyte (left lane, 1) and from an oocyte co-expressing P2X₄ receptor and PrP-3F4 (right lane, 2). Numbers on the right are molecular weights in kDa. (b) Fluorescence microscopy of an oocyte co-expressing P2X₄ receptor and PrP-GFP (green), bar = 10 μM.

(a)

(b)