Genetic Association between Akt1 Polymorphisms and Alzheimer's Disease in a Japanese Population

Table 1

Genotypic frequencies of SNPs of the Akt1 gene.

SNP	Location	Genotype	AD	Controls	𝑃 value	HWE 𝑃 value
		A/A	3	3
rs113021411	intron 1	A/C	33	45	0.002*	AD: 0.93
		C/C	142	81		Controls: 0.68
		C/C	77	22
rs2494746	intron 3	C/G	72	85	0.00002*	AD: 0.52
		G/G	29	22		Controls: 0.04*
		C/C	78	22
rs2494743	intron 3	C/T	71	85	0.00001*	AD: 0.47
		T/T	29	22		Controls: 0.04*
		A/A	27	20
rs2494738	intron 3	A/G	79	68	0.3	AD: 0.93
		G/G	71	41		Controls: 0.91
		A/A	174	126
rs3730344	intron 6	A/G	4	3	0.99	AD: 0.99
		G/G	0	0		Controls: 0.99
		A/A	151	114
rs7140735	intron 13	A/G	27	13	0.17	AD: 0.88
		G/G	0	1		Controls: 0.99

𝑃^∗<0.05: Statistically significant (Fisher's exact probabilities test).